Table 3. Association of NOX4 expression with the clinicopathological characteristics of CRC.
| NOX4 expression | |||||
|---|---|---|---|---|---|
| clinicopathological feature | Category | Total (%) | Low expression (n = 36, 43.9%) | High expression (n = 46, 56.1%) | P value |
| Sex | Male | 47 (57.3) | 22 (46.8) | 25 (53.2) | |
| Female | 35 (42.7) | 14 (40.0) | 21 (60.0) | 0.539 | |
| Age(years) | < 65 | 35 (42.7) | 17 (48.6) | 18 (51.4) | |
| ≥ 65 | 47 (57.3) | 19 (40.4) | 28 (59.6) | 0.462 | |
| Tumor size | < 5 cm | 35 (42.7) | 17 (48.6) | 18 (51.4) | |
| ≥ 5 cm | 47 (57.3) | 19 (40.4) | 28 (59.6) | 0.462 | |
| Tumor location | Right hemicolon | 44 (53.7) | 17 (38.6) | 27 (61.4) | |
| Left hemicolon | 38 (46.3) | 19 (50.0) | 19 (50.0) | 0.301 | |
| T classification | T1 | 1 (1.2) | 0 (0.0) | 1 (100.0) | |
| T2 | 4 (4.9) | 4 (100.0) | 0 (0.0) | ||
| T3 | 55 (67.1) | 28 (50.9) | 27 (49.1) | ||
| T4 | 22 (26.8) | 4 (18.2) | 18(81.8) | 0.005 | |
| Lymph node metastasis | Absent | 41 (50.0) | 23 (56.1) | 18 (43.9) | |
| Present | 41 (50.0) | 13 (31.7) | 28 (68.3) | 0.026 | |
| Distant metastasis | Absent | 73 (89.0) | 36 (49.3) | 37 (50.7) | |
| Present | 9 (11.0) | 0 (0.0) | 9 (100.0) | 0.014 | |
| Histological differentiation | Well/moderate | 60 (73.2) | 25 (41.7) | 35 (58.3) | |
| poor | 22 (26.8) | 11 (50.0) | 11 (50.0) | 0.500 | |
Values in parentheses indicate percentage values. Bold values indicate statistical significance, P < 0.05.