Table 2. Details of diffusion parameters.
Discovery group | Validation group | |
---|---|---|
ADC | 0.95 ± 0.15 | 0.97 ± 0.21 |
D* | 19.8 ± 7.8 | 20.5 ± 8.2 |
f | 0.16 ± 0.06 | 0.16 ± 0.07 |
D | 0.74 ± 0.07 | 0.76 ± 0.1 |
f1 | 0.12 ± 0.04 | 0.12 ± 0.04 |
f2 | 0.24 ± 0.04 | 0.25 ± 0.04 |
f3 | 0.64 ± 0.06 | 0.63 ± 0.06 |
D1 | 29 ± 9.7 | 29.9 ± 10.6 |
D2 | 0.93 ± 0.16 | 0.94 ± 0.17 |
D3 | 0.63 ± 0.1 | 0.62 ± 0.09 |
α | 0.68 ± 0.09 | 0.66 ± 0.08 |
DDC | 1.06 ± 0.19 | 1.11 ± 0.22 |
Dk | 1.19 ± 0.21 | 1.23 ± 0.24 |
K | 0.78 ± 0.12 | 0.79 ± 0.11 |
tumor size in 1st scan | 7.26 ± 4.32 | 7.55 ± 4.58 |
tumor size in 2nd scan | 9.78 ± 6.51 | 9.81 ± 6.45 |
tumor growth rate | 134.6 ± 20.1 | 130.5 ± 16.2 |
Data are mean ± standard deviation. ADC: apparent diffusion coefficient (×10−3 mm2/s), D: true diffusion coefficient (× 10−3 mm2/s), f: perfusion fraction (× 102%), D*: fast diffusion coefficient (×10−3 mm2/s), f1: perfusion-related diffusion fraction (× 102%), f2: intermediate diffusion fraction (×102%), f3: slow diffusion fraction (×102%), D1: perfusion-related diffusion coefficient (×10−3 mm2/s), D2: intermediate diffusion coefficient (×10−3 mm2/s), D3: slow diffusion coefficient (×10−3 mm2/s), α: diffusion heterogeneity (dimensionless), DDC: distributed diffusion coefficient (×10−3 mm2/s), K: kurtosis value (dimensionless), Dk: kurtosis corrected diffusion coefficient (×10−3 mm2/s), tumor size in 1st scan (cm2), tumor size in 2st scan (cm2), tumor growth rate (%). The directly measured tumor size and its growth rate.