Skip to main content
. 2017 Apr 6;8(20):33683–33693. doi: 10.18632/oncotarget.16898

Figure 2. Raloxifene did not affect the phosphorylation of STAT3 on Tyr705 or other STATs induced by other cytokines.

Figure 2

Raloxifene did not inhibit the phosphorylation of STAT3 on Tyr705 induced by (A) LIF, did not inhibit the phosphorylation of STAT1 on Tyr701 induced by IFN-γ (B) and IFN-α (C), and did not inhibit STAT6 phosphorylation on Tyr641 induced by IL-4 (D) in Hep-3B liver cancer cells. With pretreated with Raloxifene for 2 h followed by cytokines inducing for another 30 min, western blot was used to evaluate the phosphorylation of STAT3, STAT1 and STAT6.