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(A) The expression levels of ERK, p-ERK, MMP2 and Vimentin were analyzed in MCF-7/AKR1B10 cells. (B and C) The AKR1B10-induced levels of p-ERK, MMP2 and vimentin were interrupted by ERK inhibitor PD98059 (10μM). Scram: Scramble siRNA; siRNA: AKR1B10 siRNA; MCF-7/V: MCF-7/Vector; MCF-7/A: MCF-7/AKR1B10.
