Table 1. Characteristics of studies included in meta-analysis.
| Author | Year | Region | Study design | NOS Score | EGFR mutant and wild type | EGFR 19Del and L858R | References | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| M/W number | ORR | DCR | 19Del/L858 number | ORR | DCR | ||||||
| Zhao Q | 2011 | China | R | 6 | 5/14 | Y | Y | 4/1 | Y | N | [20] |
| Zen Xiao-Mei | 2013 | China | R | 6 | 15/3 | Y | Y | N | N | [38] | |
| Yang Xin-Jie | 2013 | China | R | 6 | 18/2 | Y | Y | 10/8 | Y | Y | [39] |
| Yang S | 2016 | China | R | 7 | 32/55 | Y | N | N | N | [31] | |
| Wei Feng-Lu | 2015 | China | R | 6 | 15/15 | Y | Y | N | N | [40] | |
| Wang Tao | 2016 | China | R | 7 | 38/29 | Y | Y | 15/16 | Y | N | [32] |
| Tan Fen-Lai | 2012 | China | R | 7 | 249/101 | Y | Y | 72/88 | Y | Y | [35] |
| Sun Jing | 2014 | China | R | 7 | 34/10 | Y | Y | N | N | [41] | |
| Song Zheng-Bo | 2013 | China | R | 6 | 36/13 | Y | Y | N | N | [42] | |
| Shao L | 2014 | China | R | 7 | 12/16 | Y | Y | N | N | [43] | |
| Ren G-J | 2011 | China | R | 5 | 7/7 | Y | Y | 3/4 | Y | Y | [44] |
| Pang Lin-Rong | 2014 | China | R | 6 | 33/18 | Y | Y | 19/13 | Y | Y | [21] |
| Nong Jin-Yin | 2013 | China | R | 6 | 23/9 | Y | Y | 14/9 | Y | N | [22] |
| Na Qin | 2013 | China | R | 6 | 35/11 | Y | Y | N | N | [16] | |
| Ma Xiang-Leiei | 2014 | China | R | 7 | 40/14 | Y | Y | N | N | [45] | |
| Liang Shao-Ping-Ping | 2015 | China | R | 5 | 10/2 | Y | Y | N | N | [46] | |
| Li Xi | 2012 | China | R | 6 | 23/36 | Y | Y | 55/40 | Y | Y | [34] |
| Li Xi | 2015 | China | R | 6 | 99/25 | Y | Y | 13/9 | Y | Y | [18] |
| Li Ran | 2013 | China | R | 5 | 23/7 | Y | Y | 17/6 | Y | Y | [47] |
| He Xiao-Tin | 2015 | China | R | 6 | 33/13 | Y | Y | N | N | [48] | |
| He Chun-Xiao | 2012 | China | R | 7 | 1/4 | Y | Y | N | N | [49] | |
| Guo Lei | 2016 | China | R | 7 | 21/6 | Y | Y | N | N | [50] | |
| Gu A | 2013 | China | R | 5 | 4/2 | Y | Y | N | N | [51] | |
| Chen Xiao-Feng | 2014 | China | R | 6 | 19/63 | Y | Y | N | N | [33] | |
| Zhang Xiao-Xue | 2016 | China | R | 7 | N | N | 60/44 | Y | N | [7] | |
| Shen Yan-Wei | 2016 | China | R | 6 | N | N | 21/14 | Y | Y | [17] | |
Abbreviations: Y, Yes; N, NO; M, Mutation; W, wild type; Del, deletion; R, Retrospective study; NOS, Newcastle-Ottawa Scale; ORR, Objective Response Rate; DCR, disease control rate.