Table 1. Photosensitizers for photodynamic therapy approved in Japan.
Photosensitizer | 1st generation | 2nd generation | |
---|---|---|---|
Porfimer sodium | Talaporfin sodium | ||
Trade name | Photofrin | Laserphyrin | |
Target diseases | Lung cancer, esophageal cancer, gastric cancer, uterus cervical cancer | Lung cancer, brain tumor, esophageal cancer | |
Laser devise | Excimer dye laser (145×69×131 cm3, 600 kg) | Semiconductor laser (PD Laser) (40×40×21 cm3, 14 kg) | |
Wavelength (nm) | 630 nm | 664 nm | |
Chemical structure |