Table 5.
Odds ratios (OR) of oral and pharyngeal cancer and corresponding 95% confidence intervals (CI) according to quartiles of energy-adjusted dietary inflammatory index (E-DII), among 946 cases and 2492 controls, in strata of selected covariates. Italy, 1992–2009.
| Cases/Controls | E-DII quartiles, OR (95% CI)a | p value for trend | p value for homogeneity | ||||
|---|---|---|---|---|---|---|---|
| −5.29, −1.19 | −1.18, −0.31 | −0.30, 0.73 | 0.74, 7.66 | ||||
| Age (years) | 0.52 | ||||||
| <60 | 503/1317 | 1 b | 0.84 (0.54, 1.8) | 1.41 (0.94, 2.11) | 1.45 (0.96, 2.17) | 0.02 | |
| ≥60 | 443/1175 | 1 b | 1.07 (0.70, 1.62) | 1.53 (1.03, 2.27) | 2.12 (1.42, 3.16) | <0.0001 | |
| Sex | 0.03 | ||||||
| Male | 756/1497 | 1 b | 0.72 (0.50, 1.04) | 1.40 (1.00, 1.96) | 1.38 (0.98, 1.96) | 0.002 | |
| Female | 190/995 | 1 b | 1.69 (0.98, 2.91) | 1.66 (0.95, 2.89) | 3.30 (1.95, 5.57) | <0.0001 | |
| Education (years)c | 0.38 | ||||||
| <7 | 553/1272 | 1 b | 1.31 (0.86, 2.00) | 1.67 (1.11, 2.52) | 2.07 (1.37, 3.13) | 0.0003 | |
| ≥7 | 388/1209 | 1 b | 0.64 (0.41, 1.00) | 1.41 (0.95, 2.10) | 1.62 (1.09, 2.41) | 0.0002 | |
| Alcohol (drinks/week) | 0.76 | ||||||
| <28 | 364/1862 | 1 b | 1.00 (0.68, 1.45) | 1.49 (1.05, 2.12) | 1.85 (1.30, 2.63) | <0.0001 | |
| ≥28 | 582/630 | 1 b | 1.07 (0.67, 1.73) | 1.84 (1.18, 2.88) | 2.28 (1.46, 3.58) | 0.0003 | |
| Tobacco smokingc | 0.37 | ||||||
| Non-smoker | 137/1077 | 1 b | 1.84 (1.02, 3.33) | 1.88 (1.04, 3.41) | 3.06 (1.69, 5.51) | 0.0003 | |
| Ex-smoker | 255/761 | 1 b | 0.90 (0.53, 1.52) | 1.72 (1.05, 2.80) | 1.47 (0.88, 2.44) | 0.04 | |
| Current smoker | 550/649 | 1 b | 0.70 (0.43, 1.15) | 1.35 (0.86, 2.14) | 1.72 (1.09, 2.72) | <0.0001 | |
a
Adjusted for age, sex, centre, year of interview, education, body mass index, tobacco smoking, alcohol consumption, and non-alcohol energy intake.
b
Reference category.
c
The sum does not add up to the total because of some missing values