Figure 2. Representative haematoxylin & eosin (H&E) and immunohistochemical staining (IHC) of porcine corneal grafts in anti-CD40 Ab-treated primate.
(A) Staining of a surviving graft showed less inflammatory cell infiltration without any graft edema (Top; H&E, bottom; IHC using anti-CD 68 Ab; arrowheads indicate donor-recipient junction; x40 and x200). (B) Staining of a rejected graft in a primate without anti-CD40 Ab treatment (control, steroid treated primate) showed severe edema and inflammatory cell infiltration around the donor-recipient junction (Top; H&E, bottom; IHC using anti-CD 68 Ab; arrowheads indicate the donor-recipient junction; magnification x40 and x200).