Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 19;36(23):3263–3273. doi: 10.1038/onc.2016.471

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Spontaneous relapse after suppression of Ras oncogene expression in mice with NRAS(V12)-driven AML. White blood cell (WBC) counts of leukemic SCID beige mice with NRAS(V12)-dependent (NRD) AML rapidly decline after doxycycline (Dox)-mediated suppression of NRAS(V12) expression. Two of five mice spontaneously relapsed with NRI AML (NRI1 and NRI1 AMLs) despite continued Dox treatment.