Table 1.
Clinical characteristics of ESRD patients and healthy control subjects.
| ESRD (n = 50) | Control (n = 28) | p-value | |
|---|---|---|---|
| Clinical variables | |||
| Age (years) | 53.2 ± 12.8 | 52.9 ± 9.1 | 0.910 |
| Male gender | 32 (64.0%) | 18 (64.3%) | 1.000 |
| CAD | 9 (18.0%) | 0 (0%) | 0.023* |
| Hypertension | 38 (82.6%) | 5 (17.9%) | <0.001* |
| DM | 14 (31.1%) | 1 (3.6%) | 0.006* |
| Dyslipidemia | 6 (13.0%) | 6 (21.4%) | 0.352 |
| Current Smoker | 5 (10.0%) | 6 (21.4%) | 0.188 |
| BMI (kg/m2) | 23.6 ± 3.4 | 24.0 ± 2.3 | 0.566 |
| SBP (mmHg) | 149.4 ± 22.6 | 119.3 ± 9.5 | <0.001* |
| DBP (mmHg) | 81.7 ± 11.4 | 77.3 ± 7.9 | 0.078 |
| Anuria | 35 (70%) | ||
| Hemodialysis | 22 (44%) | ||
| Peritoneal dialysis | 28 (56%) | ||
| Dialysis duration (year) | 5.5 ± 6.3 | ||
| Laboratory variables | |||
| WBC count (×103/μL) | 6.3 ± 2.0 | 6.1 ± 1.5 | 0.566 |
| Hemoglobin (g/dL) | 11.0 ± 1.5 | 14.5 ± 1.8 | <0.001* |
| Glucose (mg/dL) | 102.0 ± 38.9 | 95.1 ± 17.0 | 0.380 |
| Total cholesterol (mg/dL) | 157.9 ± 33.4 | 193.5 ± 29.2 | <0.001* |
| HDL cholesterol (mg/dL) | 46.8 ± 17.3 | 53.0 ± 12.6 | 0.105 |
| Triglyceride (mg/dL) | 97.2 ± 51.3 | 149.3 ± 159.3 | 0.104 |
| Uric acid (mg/dL) | 6.1 ± 1.6 | 4.9 ± 1.3 | 0.002* |
| hsCRP (mg/L) | 3.1 ± 6.8 | 1.0 ± 0.9 | 0.074 |
| BUN (mg/dL) | 58.3 ± 23.6 | 15.1 ± 4.1 | <0.001* |
| Creatinine (mg/dL) | 10.6 ± 3.7 | 1.0 ± 0.2 | <0.001* |
| Albumin (g/dL) | 3.9 ± 0.5 | 4.6 ± 0.2 | <0.001* |
| Calcium (mg/dL) | 9.1 ± 0.7 | ||
| Phosphorus (mg/dL) | 5.0 ± 1.5 | ||
| Calcium-phosphorus product (mg2/dL2) | 45.6 ± 13.9 | ||
ESRD, end-stage renal disease; CAD, coronary artery disease; DM, diabetes mellitus; BMI, body mass index; BUN, blood urea nitrogen; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; HDL, high-density lipoprotein; hsCRP, high-sensitivity C-reactive protein. Data are presented as mean ± SD or n (%). *A p-value < 0.05 was considered statistically significant.