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. 2017 Jun 8;7:3029. doi: 10.1038/s41598-017-03582-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Images in a 60-year-old patient with breast invasive ductal carcinoma, no axillary lymph node metastasis (LNM), histologic grade II, positive estrogen receptor (ER), negative progesterone receptor (PR), and negative C-erbB-2. (a) A solid, heterogeneous hypoechogenicity, and poorly defined margin lesion (arrows) is shown on ultrasound (US). (b) Poor internal flow (i.e. dotted signals on color Doppler US) is found on color Doppler flow image (arrows). (c) Virtual touch tissue imaging (VTI) score of the lesion (arrows) is 3. (d) On virtual touch tissue imaging & quantification image, the lesion (arrows) is heterogeneous with a mean SWS value of 8.24 m/s. (e) Pathological examination confirms the diagnosis of invasive ductal carcinoma (Hematoxylin-eosin stain, x200). (f) Pathological examination confirms the diagnosis of normal lymph node (Hematoxylin-eosin stain, x200).