Table 1.
Distances separating the IgH subregions, Vh1, Vh9/4, and Cα in pro-B cells, RAG-deficient pro-B cells, CD8+ T cells, and in E2A-deficient hematopoietic progenitor cells
| Pro-B | RAG2−/− | CD8+ T | E2A−/− | |
|---|---|---|---|---|
| n | 114+ | 372 | 245 | 200 |
| Vh1-Vh9/4 | 0.29 ± 0.14*** | 0.27 ± 0.11*** | 0.38 ± 0.20 | 0.33 ± 0.15 |
| Vh9/4-Cα | 0.33 ± 0.19*** | 0.29 ± 0.12*** | 0.42 ± 0.23 | 0.42 ± 0.23 |
| Vh1-Cα | 0.38 ± 0.21*** | 0.37 ± 0.14*** | 0.56 ± 0.28 | 0.51 ± 0.24 |
| Vh1-Vh9/4 + Vh9/4-Cα | 0.62 ± 0.25 | 0.56 ± 0.17 | 0.81 ± 0.31 | 0.74 ± 0.28 |
Shown are averages ± SD expressed in microns. (n) The number of cells analyzed for each cell type. (+) Some cells may have undergone Ig V(D)J recombination. (***) p < 0.001 when compared with CD8+ T cells.