Table 3. Correlation analyses between baseline individual parameters and PCSK9 percent change.
| Parameter | Mean ± SD | Spearman’s rho | P value |
|---|---|---|---|
| Age (years) | 63.82±8.06 | −0.039 | 0.770 |
| BMI (kg/m2) | 23.95±1.88 | 0.095 | 0.469 |
| TC (mmol/L) | 6.39±1.27 | −0.004 | 0.978 |
| TG (mmol/L) | 2.32±0.82 | 0.053 | 0.690 |
| HDL-C (mmol/L) | 1.03±0.23 | −0.075 | 0.567 |
| LDL-C (mmol/L) | 4.08±0.87 | 0.113 | 0.390 |
| ΔLDL-C (%) | −(50.04±23.60) | −0.949 | 0.000* |
| PCSK9 (ng/mL) | 309.32±132.84 | −0.554 | 0.000* |
Parameters listed in the above table are all at baseline. *, P<0.05; BMI, body mass index; TC, total cholesterol; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; ΔLDL-C (%) = [(LDL-C at 14th day − LDL-C at baseline) / LDL-C at baseline]×100%. PCSK9, proprotein convertase subtilisin kexin type 9.