Table 4. The reports of the surgically resected pulmonary pleomorphic carcinoma.
Reports | Patients number | Prognostic factors (overall survival) | Progression free survival factors | Others |
---|---|---|---|---|
Fishback (1994) | 78 | Pathological stage, tumor size, lymph node metastasis | - | Type of epithelial components was no prognostic factor |
Yuki (2007) | 45 | Lymph node metastasis | lymph node metastasis | - |
Yamamoto (2007) | 21 | None | lymph node metastasis | - |
Mochizuki (2008) | 70 | Pathological stage, lymph node metastasis, necrosis | - | type of epithelial components was no prognostic factor |
Ito (2010) | 22 | Surgical resection | - | resistant to chemotherapy (gefitinib was partial response for 1 patient) |
Kaira (2010) | 17 | Surgical resection | - | 3/17 patients were EGFR mutation positive |
Tsubata (2012) | 75 | VEGF expression | - | - |
Chen (2012) | 26 | Pleural invasion, pathological edge | None | - |
Miyahara (2015) | 62 | Positive for ZEB1 expression | - | - |
Okuda (this report) | 24 | Lymph node metastasis, vascular invasion | lymph node metastasis, type of epithelial components, vascular invasion | Neo-adjuvant therapy |
CBDCA+PTX for 4 patients/SD, Ef1a about all | ||||
CDDP+VNR for 1 patient/PR, Ef2a |