Figure 2.

Human Y chromosome pericentromeric segmental duplications. A simplified version of the 554-kb sequenced contig is shown in the middle. The two large boxes represent the genomic segments composed of interchromosomal duplications, the small box that of intrachromosomal duplications. Other chromosomes are represented as horizontal black lines, above and below. Centromeres and acrocentric p arms are indicated as tiny boxes. All diagonal lines represent pairwise sequence comparisons ≥10 kb of DNA. The majority of Y pericentromeric duplications localize to the pericentromeric regions of autosomes. On chromosomes 2 and 4, the ancestral pericentromeric regions also show significant pairwise alignments. The coordinates are based on the published NCBI human genome assembly (January 2004, Build 34, Vers. 2).