Table 2.
Genic paralogies in pericentromeric Yq11
| Region of homology | Gene | Name | GenBank acc. no. | Ancestral locus | Reference |
|---|---|---|---|---|---|
| Degenerated processed pseudogenes | |||||
| 55219-58321 | FLJ42128 | Testis cDNA clone | AK124122 | Unknown | Unpublished |
| 68740-70354 | LOC339742 | Image cDNA clone | BC045732 | Chr 2 | Unpublished |
| 100202-106214 | ASNS | Asparagine synthetase | NM_133436 | Chr 7q21 | Arfin et al. 1983 |
| 142459-148130 | FLJ35140 | Kazusa cDNA clone | AK092459 | Unknown | Unpublished |
| 164406-174880 | FLJ00310 | Kazusa cDNA clone | AK090412 | Chr 1 | Unpublished |
| 296713-299847 | PABPC1 | Poly(A) binding protein, cytoplasmic 1 | NM_002568 | Chr 8q23 | Grange et al. 1987 |
| 357596-359239 | ARP3ß | Actin-related protein 3-beta | NM_020445 | Chr 7q32-36 | Machesky and Gould 1999 |
| 407551-409679 | TRIM43 | Tripartite motif-containing 43 | NM_138800 | Chr 2 | Unpublished |
| ESTs | |||||
| 32480-33082 | Hs.252460 | UNIGENE EST cluster | / | Chr 11 | Unpublished |
| 236680-242264 | THC1666755 | TIGR EST cluster | / | Unknown | Unpublished |
| Genes with partial exon-intron structure | |||||
| 46985-47778 | AF038169 | IMAGE cDNA clone | BC043584 | Chr 1 | Unpublished |
| 134919-135544 | C21orf81 | Chromosome 21 unknown ORF 81 | AF426257 | Chr 21 | Reymond et al. 2002 |
| 302288-347418 | LOC150159 | CG10806-like IMAGE cDNA clone | NM_139173 | Chr 4 | Unpublished |
| 374270-380489 | CHEK2 | CHK2 checkpoint homolog | NM_007194 | Chr 22q12 | Matsuoka et al. 1998 |
| 435493-435986 | MGC32713 | IMAGE cDNA clone | BC034141 | Unknown | Unpublished |
| Potential coding gene | |||||
| 115523-120823 | FLJ00219 | Kazusa cDNA clone | AK074146 | Chr 13 | Unpublished |
| 115523-176727 | FLJ35473 | Kazusa cDNA clone | AK092792 | Unknown | Unpublished |
| 115523-176733 | FLJ39663 | Kazusa cDNA clone | AK096952 | Unknown | Unpublished |
| 115520-176692 | pp5644 | cDNA clone | AF289559 | Unknown | Unpublished |
| 268641-269264 | DUX1 | Double homeobox, 1 | NM_012146 | 4q35 | Ding et al. 1998 |
| 276644-276976 | DUX1 | Double homeobox, 1 | NM_012146 | 4q35 | Ding et al. 1998 |
| 283281-283613 | DUX1 | Double homeobox, 1 | NM_012146 | 4q35 | Ding et al. 1998 |
| 294054-294476 | DUX1 | Double homeobox, 1 | NM_012146 | 4q35 | Ding et al. 1998 |
| 357403-359228 | FKSG74 | FKSG74 | AY026352 | Chr 16 | Unpublished |
The position of each feature within the 554kb contiguous sequence is given, together with the accession number and EST cluster information. Unknown ancestral locus indicates either that BAC clones corresponding to that sequence are not chromosomally assigned or a corresponding genomic sequence is not available. References and ancestral locus of each genic paralogy is shown.