Table 2. Main characteristics of the included studies.
Author | Year | Number of patients (n) | N stage | PORT | Dose (Gy) | Dose per fraction (Gy) | PCI | End-point | ||
---|---|---|---|---|---|---|---|---|---|---|
N0/N1/N2 | Yes | No | Yes | No | ||||||
Bischof (15) | 2007 | 39 | 23/16/0 | 16 | 23 | 50–60 | 2 | 21 | 18 | OS |
Yu (16) | 2010 | 243 | 243/0/0 | 38 | 205 | NR | NR | NR | NR | OS |
Liu (17) | 2014 | 143 | 58/28/57 | 53 | 90 | 40–60 | 1.8–2 | 6 | 137 | OS, LRR rate |
Zhang (18) | 2015 | 55 | 15/20/20 | 23 | 32 | 45–60 | 2 | 10 | 45 | OS, DFS, LRR rate |
Wong (19) | 2016 | 3,017 | 2,032/603/382 | 448 | 2,569 | 54 | NR | NR | NR | OS |
PORT, postoperative radiotherapy; OS, overall survival; LRR, local regional recurrence; DFS, disease-free survival; NR, Not reported.