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. 2017 Jun 8;7:3052. doi: 10.1038/s41598-017-03164-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The positive correlation between G6PD and CD133 expression levels in HCC patients. (A,B) The expression of G6PD and CD133, respectively, in patients with HCC by real-time PCR. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01 and ***P < 0.001, using Student’s t-test. (C–F) Kaplan-Meier analysis of overall survival (C and D) and disease-free survival (E and F) in 37 HCC patients with low or high G6PD (C and E) or CD133 (D and F) expression. The P values were calculated using the log rank test. (G) Pearson correlation analysis of G6PD and CD133 mRNA levels in tumor tissues.