Table 2.

Frequency of base substitutions observed in int1 h and flanking sequences of different pairs of species

	Int1 h			Flanking sequence
Species pairs	d	nt	pro	d	nt	pro	P value
H + C	3	2082	0.00144	51	6941	0.00735	<0.001*
H + A	99	2080	0.0476	200	3516	0.0568	0.131
H + R	96	2082	0.0461	233	4409	0.0528	0.239
C + A	96	2080	0.0461	185	3465	0.0534	0.260
C + R	93	2082	0.0447	218	4366	0.0499	0.390
A + R	29	2092	0.0138	59	3516	0.0168	0.460

(H) human, (C) chimpanzee, (A) African Green monkey, (R) Rhesus monkey; (d) number of divergences, (nt) number of aligned nucleotides excluding sites of insertion/deletion mutations, (pro) proportion of divergence; P value is result of Normal test of equal proportions involving int1 h and flanking sequences; ^*statistically significant difference.