Table 3.
Output of the combined pharmacology–epidemiology modules. Median number of infected individuals per population of 100 000 by therapeutic intervention, transmissibility (R0), and % of infected individuals treated with oseltamivira
| % treated | No treatment | 75 mg BID | 150 mg BID |
|---|---|---|---|
| Low transmissibility (R 0 = 1.9) | |||
| 37 068 | |||
| 25% | ‐‐ | 7846 (7846–20 354) | 5311 (5311–1,6303) |
| 50% | ‐‐ | 2252 (2252–12 279) | 1357 (1357–7202) |
| 80% | ‐‐ | 1349 (1349–8504) | 741 (741–4891) |
| High transmissibility (R 0 = 2.7) | |||
| 67 512 | |||
| 25% | ‐‐ | 60 397 (60397–71 149) | 53 032 (53032–59 498) |
| 50% | ‐‐ | 41 331 (41331–55 660) | 31 700 (31700–37 024) |
| 80% | ‐‐ | 20 941(20941–40 616) | 12 881 (12881–14 665) |
BID, twice daily; R0, the basic reproductive number.
a
median (25th and 75th % of viral shed) simulation are reported in this table. Note: 25th and 50th percentile identical given right skewed distribution.