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(a) The general reaction scheme of decarboxylative halogenation (R=unspecified alkyl group, Hal=unspecified halogen atom). (b) Desired enantioselective synthesis of non-racemic alkyl halides from racemic carboxylic acids. (c) Chiral amine-catalysed enantioselective decarboxylative chlorination of β-ketocarboxylic acids.
