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. 2017 Jun 5;8:15600. doi: 10.1038/ncomms15600

Figure 5. Stereospecific derivatization of α-chloroketones.

Figure 5

(a) SN2 reaction of 2a with either sodium azide or sodium thiolates as the nucleophiles (DMSO=dimethyl sulfoxide, EtOAc=ethyl acetate, Boc=tert-butoxycarbonyl group). (b) Enantioselective synthesis of the N-protected Cathinone (DMF=N,N-dimethylformamide).