Table 2. Cox and exact logistic regression models for protection against all T/F Genomes, A/K-only genomes, or non-A/K genomes in the RLD challenge study.
Group | No. of animals | Log-rank test (P-value) |
Cox model |
Exact logistic regression model |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Haz. Ratio | Lower 95% CI | Upper 95% CI | P value | Odds ratio | Lower 95% CI | Upper 95% CI | P value | ||||
Total Infections | Sham | 12 | Ref. | Ref. | Ref. | ||||||
Ad35/Ad26 | 12 | 0.0092 | 0.194 | 0.051 | 0.735 | 0.016 | 0.077 | 0.005 | 0.647 | 0.0123 | |
Ad35/Ad26/Env | 12 | 0.0010 | 0.114 | 0.024 | 0.541 | 0.006 | 0.049 | 0.003 | 0.454 | 0.0033 | |
All versus Sham | 24 versus 12 | 0.0002 | 0.152 | 0.049 | 0.464 | 0.001 | 0.059 | 0.005 | 0.393 | 0.0011 | |
Non AK only | Sham | 11 | Ref. | Ref. | Ref. | ||||||
Ad35/Ad26 | 12 | 0.0112 | 0.161 | 0.033 | 0.784 | 0.024 | 0.0867 | 0.0058 | 0.7444 | 0.0202 | |
Ad35/Ad26/Env | 12 | 0.0002 | 0.0326 | 0 | 0.2711 | 0.0007 | |||||
All versus Sham | 24 versus 11 | 0.0001 | 0.076 | 0.016 | 0.378 | 0.001 | 0.0400 | 0.003 | 0.3137 | 0.0005 | |
AK only | Sham | 11 | Ref. | Ref. | Ref. | ||||||
Ad35/Ad26 | 12 | 0.446 | 0.368 | 0.032 | 4.252 | 0.424 | 0.425 | 0.006 | 9.423 | 0.932 | |
Ad35/Ad26/Env | 12 | 0.697 | 0.682 | 0.091 | 5.133 | 0.710 | 0.904 | 0.055 | 14.949 | 1.000 | |
All versus Sham | 24 versus 11 | 0.494 | 0.531 | 0.084 | 3.342 | 0.500 | 0.651 | 0.063 | 9.053 | 1.000 |
The bold entries indicate significant P values.