TABLE 1.

β-Chemokines are produced by PBMCs in the presence of HIV-specific IgG^a

Protein	PBMCs		CD4+ lymphocytes
	HIV-positive IgG	HIV-negative IgG	HIV-positive IgG	HIV-negative IgG
MIP-1α	908 ± 184	280 ± 58	233 ± 30	226 ± 36
MIP-1β	3,901 ± 321	1,408 ± 589	1,012 ± 224	402 ± 239
RANTES	4,485 ± 1,147	2,041 ± 320	806 ± 286	1,171 ± 205

^aHIV_92US657 (4,500 TCID₅₀) was incubated with HIV antibody-positive or -negative polyclonal IgG (0.5 mg/ml) and added to PHA-stimulated PBMCs or CD4⁺ lymphocytes; virus and IgG were washed off 4 days later. β-Chemokines were measured in supernatant fluid by ELISA 7 days postinfection; data are in picograms per milliliter and represent means ± SE of six experiments. Results with HIV-positive IgG on PBMCs (boldface type) are significantly higher (P ≤ 0.05) than for other conditions.