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. 2017 Jun 8;14:70. doi: 10.1186/s12978-017-0334-1

Table 2.

Complications and side effects associated with IUD insertion and tubal sterilization over time

Copper IUD LNG IUD Tubal Sterilization
Complications/Side Effect n (%) n (%) n (%)
Amenorrhea (ICD-9 626.0)
 Total (2006–2011) 2385 (8.99)ab 9077 (7.53)ac 7050 (11.67)bc
 2006 308 (8.92) 941 (7.82) 1638 (11.00)
 2007 381 (10.02) 1278 (7.61) 1614 (10.93)
 2008 412 (9.21) 1873 (7.72) 1700 (11.59)
 2009 448 (9.20) 1845 (7.44) 1658 (11.14)
 2010 452 (8.62) 1518 (7.36) 1429 (10.73)
 2011 384 (8.20) 1622 (7.36) 1371 (10.92)
P Value 0.0775 0.4191 0.2768
Anemia (ICD-9 280.xx)
 Total (2006–2011) 595 (2.24)b 2832 (2.35)c 2003 (3.32)bc
 2006 67 (1.94) 279 (2.32) 435 (2.92)
 2007 78 (2.05) 386 (2.30) 433 (2.93)
 2008 106 (2.37) 538 (2.22) 492 (3.35)
 2009 119 (2.44) 600 (2.42) 513 (3.45)
 2010 135 (2.57) 512 (2.48) 481 (3.61)
 2011 90 (1.92) 517 (2.35) 469 (3.73)
P Value 0.1496 0.5243 0.0001
Dysmenorrhea (ICD-9 625.3)
 Total (2006–2011) 733 (2.76)ab 3909 (3.24)ac 2491 (4.12)bc
 2006 90 (2.61) 378 (3.14) 587 (3.94)
 2007 85 (2.50) 566 (3.37) 591 (4.00)
 2008 132 (2.95) 723 (2.98) 598 (4.08)
 2009 139 (2.86) 807 (3.25) 647 (4.35)
 2010 137 (2.61) 692 (3.35) 649 (4.87)
 2011 140 (2.99) 743 (3.37) 606 (4.82)
P Value 0.6388 0.1234 <0.0001
Heavy Menstrual Bleeding (ICD-9 626.2)
 Total (2006–2011) 1370 (5.16)ab 10 204 (8.46)ac 7328 (12.13)bc
 2006 204 (5.91) 1048 (8.71) 1687 (11.33)
 2007 198 (5.21) 1406 (8.37) 1750 (11.85)
 2008 224 (5.01) 1846 (7.60) 1922 (13.10)
 2009 256 (5.26) 1992 (8.03) 2045 (13.74)
 2010 261 (4.98) 1881 (9.11) 2006 (15.07)
 2011 227 (4.85) 2031 (9.22) 1971 (15.69)
P Value 0.3527 <0.0001 <0.0001
Infection (ICD-9 998.5x)
 Total (2006–2011) 15 (0.06) 88 (0.07)c 18 (0.03)c
 2006 4 (0.12) 12 (0.10) 2 (0.01)
 2007 1(0.03) 14 (0.08) 2 (0.01)
 2008 6 (0.13) 15 (0.06) 7 (0.05)
 2009 2 (0.04) 25 (0.10) 4 (0.03)
 2010 0 (0.00) 14 (0.07) 4 (0.03)
 2011 2 (0.04) 8 (0.04) 5 (0.04)
P Value 0.0543 0.1255 0.4301
Menorrhagia (ICD-9 627.0)
 Total (2006–2011) 53 (0.20)ab 528 (0.44)ac 410 (0.68)bc
 2006 12 (0.35) 48 (0.40) 88 (0.59)
 2007 6 (0.16) 58 (0.35) 94 (0.64)
 2008 11 (0.25) 84 (0.35) 92 (0.63)
 2009 12 (0.25) 89 (0.36) 119 (0.80)
 2010 8 (0.15) 121 (0.59) 121 (0.91)
 2011 4 (0.09) 128 (0.58) 126 (1.00)
P Value 0.1181 <0.0001 <0.0001
Ovarian Cyst (ICD-9 620.2)
 Total (2006–2011) 1157 (4.36)ab 6340 (5.26)ac 4324 (7.16)bc
 2006 140 (4.05) 539 (4.48) 1045 (7.02)
 2007 155 (4.08) 786 (4.68) 990 (6.70)
 2008 211 (4.72) 1268 (5.22) 1076 (7.34)
 2009 209 (4.29) 1400 (5.64) 1039 (6.98)
 2010 223 (4.25) 1142 (5.53) 1003 (7.53)
 2011 219 (4.68) 1205 (5.47) 910 (7.25)
P Value 0.5197 <0.0001 0.0975
Pelvic Inflammatory Disease (ICD-9 614.xx–616.xx)
 Total (2006–2011) 5053 (19.05)ab 19 063 (15.81)ac 11 162 (18.48)bc
 2006 13 (0.38) 40 (0.33) 64 (0.43)
 2007 12 (0.32) 53 (0.32) 66 (0.45)
 2008 23 (0.51) 74 (0.30) 69 (0.47)
 2009 15 (0.31) 60 (0.24) 54 (0.37)
 2010 12 (0.23) 49 (0.24) 41 (0.31)
 2011 18 (0.38) 58 (0.26) 25 (0.20)
P Value 0.282 0.3727 0.02
Pelvic Pain (ICD-9 625.9, 789.00)
 Total (2006–2011) 3222 (12.15)ab 13 891 (11.52)ac 8323 (13.78)bc
 2006 384 (11.12) 1395 (11.60) 1987 (13.35)
 2007 466 (12.25) 1915 (11.41) 1997 (13.52)
 2008 519 (11.60) 2729 (11.24) 1976 (13.47)
 2009 627 (12.88) 2897 (11.68) 2117 (14.23)
 2010 661 (12.60) 2419 (11.72) 1881 (14.13)
 2011 565 (12.07) 2536 (11.51) 1792 (14.27)
P Value 0.1449 0.617 0.0593
Perforation of Uterine Wall (ICD-9 621.8, 665.3)
 Total (2006–2011) 412 (1.55)ab 1558 (1.29)ac 387 (0.64)bc
 2006 40 (1.16) 142 (1.18) 57 (0.38)
 2007 51 (1.34) 176 (1.05) 76 (0.51)
 2008 48 (1.07) 301 (1.24) 91 (0.62)
 2009 88 (1.81) 319 (1.29) 119 (0.80)
 2010 98 (1.87) 307 (1.49) 103 (0.77)
 2011 87 (1.86) 313 (1.42) 109 (0.87)
P Value 0.0014 0.0023 <0.0001

abcChi square pairwise comparisons between groups with the same superscript, P < 0.05. The pairwise comparisons were done for the total for each complication/side effect across years 2006–2011 and not for the individual years