Table 1.
Neuronal density and cortical volume measurements from saline or LPS-injected mice
Treatment group | Average NeuN count (% saline ± SEM) |
Average cortical volume ± SEM (μm3) × 103 |
||
---|---|---|---|---|
NOX2+/+ | NOX2−/− | NOX2+/+ | NOX2−/− | |
Saline | 100 ± 3.2 | 100 ± 7.3 | 1.4 ± 0.2 | 1.14 ± 0.3 |
LPS 6 h | 103 ± 5.9 | – | 1.1 ± 0.2 | – |
LPS 24 h | 98 ± 0.8 | 109 ± 4.9 | 1.1 ± 0.1 | 1.15 ± 0.3 |
LPS 3 days | 108.1 ± 2.5 | – | 1.4 ± 0.1 | – |
LPS 1 week | 97.7 ± 2.5 | 110 ± 3.4 | 1.2 ± 0.1 | 1.27 ± 0.1 |
LPS 2 weeks | 108 ± 3.9 | – | 1.5 ± 0.1 | – |
No significant difference was detected with regard to density of neuronal cell bodies or cortical volume among any of the treatment groups in either NOX2+/+ or NOX2−/− mice