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Sequence alignments of RPN13, RPN2, and ubiquitin from higher eukaryotes. A, RPN13 alignments. Stars indicate residues not conserved between mouse and human. Blue triangles indicate residues at the RPN13-RPN2 interface. Gray triangles indicate residues at the RPN13-ubiquitin interface. B, RPN2 sequence alignment. Magenta triangles indicate residues at the RPN13-RPN2 interface. C, ubiquitin sequence alignment; magenta triangles indicate residues at the RPN13-ubiquitin interface.
