Table 1.
Patient characteristics, risk factors, and clinical presentation according to the presence of CKD
| CKD+ n = 331 (17.3%) | CKD– n = 1,577 (82.7%) | p | |
|---|---|---|---|
| Demographic data | |||
| Age, years | 71 [64–76] | 61 [56–69] | <0.001 |
| Male | 163 (49.2) | 1,066 (67.5) | <0.001 |
| Female | 168 (50.7) | 511 (32.4) | <0.001 |
| BMI | 29 [26–32] | 28.4 [25–31] | 0.043 |
| Discharge diagnosis | |||
| UA | 246 (74.3) | 1,247 (79.0) | 0.066 |
| NSTEMI | 68 (20.5) | 216 (13.6) | 0.002 |
| STEMI/LBBB | 17 (5.1) | 114 (7.2) | 0.211 |
| CAD history | |||
| Previous MI | 179 (54.0) | 734 (46.5) | 0.014 |
| Previous PCI | 203 (61.3) | 858 (54.4) | 0.024 |
| Previous CABG | 80 (24.1) | 317 (20.1) | 0.113 |
| CAD risk factors | |||
| Hypertension | 305 (92.1) | 1,331 (84.4) | <0.001 |
| Dyslipidemia | 212 (64.0) | 1,046 (66.3) | 0.464 |
| Diabetes mellitus | 167 (50.4) | 548 (34.7) | <0.001 |
| Smoking | 43 (12.9) | 418 (26.5) | <0.001 |
| Concomitant disease | |||
| Anemia | 69 (20.8) | 147 (9.3) | <0.001 |
| Cancer | 31 (9.3) | 84 (5.3) | 0.007 |
| COPD | 33 (9.9) | 84 (5.3) | 0.002 |
| PAD | 58 (17.5) | 160 (10.1) | <0.001 |
| Length of hospital stay, days | 5 [4–8] | 4 [3–6] | <0.001 |
| Left ventricular function | 50 [40–55] | 55 [46–60] | <0.001 |
| Laboratory | |||
| GFR, mL/min/1.73 m2 | 49 [40–55] | 87 [75–96] | <0.001 |
| Creatinine, mg/dL | 1.2 [1.1–1.5] | 0.8 [0.7–0.9] | <0.001 |
| Hemoglobin on admission, g/dL | 13 [12–14] | 14 [13–15] | <0.001 |
| Clinical status on admission | |||
| HR, bpm | 71 [60–80] | 70 [60–77] | 0.076 |
| SBP, mm Hg | 130 [120–145] | 130 [120–150] | 0.780 |
| CCS | |||
| II | 87 (26.2) | 508 (32.2) | 0.040 |
| III-IV | 244 (73.7) | 1,069 (67.7) | |
| KILLIP | |||
| I-II | 83 (97.6) | 321 (97.2) | 0.851 |
| III-IV | 2 (2.3) | 9 (2.7) | |
| GRACE score >140 points | 37 (77.0) | 99 (51.5) | 0.002 |
Values are median [ranges] or n (%). BMI, body mass index; UA, unstable angina; NSTEMI, non-ST-segment elevation myocardial infarction; STEMI, ST-segment elevation myocardial infarction; LBBB, left bundle branch block; CAD, coronary artery disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; PAD, peripheral artery disease; HR, heart rate; SBP, systolic blood pressure. CKD was defined as estimated GFR <60 mL/min/1.73 m2 calculated using the Modification of Diet in Renal Disease method.