Fig. 6.

Colonoscopy findings at week 18 of tacrolimus administration. The scope was inserted up to the end of the ileum. Reddening and erosion were absent at the end of the ileum (c). Bauhin's valve (a, b) was slightly dilated, and small erosion was noted. Biopsy 1: mucosal atrophy was noted in the ileocecum over the ascending colon. In the transverse colon (b) over the sigmoid colon, ulcer scars, inflammatory polyps, and partial mucosal healing were observed. Healed mucosa was noted in the rectum. Results of biopsy of erosion collected from Bauhin's valve (d): mucosa with very mild activity. Diffuse inflammatory cell infiltration (+), decrease in germinal (goblet suspicion) cells (±), regressive change of glandular epithelium (–), crypt abscess (–), disturbed gland duct arrangement (+), gland regeneration (+), Paneth cells (–).