Table 3.

Association tests for APOL1 genotypes with prevalent CAD using additive, recessive, and dominant models

Variable	Genetic model	Estimate	OR	95% CI	p value
APOL1 heterozygote	Additive, basica	–0.18	0.84	0.67–1.04	0.12
	Additive, multivariableb	–0.22	0.80	0.63–1.01	0.06
APOL1 homozygote	Additive, basica	–0.05	0.95	0.70–1.31	0.77
	Additive, multivariableb	–0.98	0.91	0.65–1.26	0.56
	Recessive, basica	0.04	1.05	0.78–1.40	0.77
	Recessive, multivariableb	0.016	1.02	0.75–1.38	0.92
APOL1 homozygote or	Dominant, basica	–0.15	0.86	0.70–1.06	0.17
heterozygote carriers	Dominant, multivariableb	–0.19	0.82	0.66–1.03	0.08

^aAdjusted for age and sex.

^bAdjusted for age, sex, BMI, type 2 diabetes status, hypertension status, smoking status, and baseline eGFR.