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Growth curve analyses of ToledoΔ15kb and ToledoΔ15kbR clones. The ToledoBAC (lane B), ToledoΔ15kb (lane Δ), and ToledoΔ15kbR (lane R) viruses were used to infect HFF cells at MOIs of 5 (A) and 0.1 (B). At the indicated days, the samples were collected and the titers of the viruses were determined.
