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Figure 3.

Figure 3.

Improved proliferation and erythroid differentiation in a steroid-treated patient. (A) Growth curves of CD34+ cells from control donors (n = 24) and a DBA patient with a deletion in chromosome 3q29 containing the RPL35A gene before (magenta; n = 2) and after (red; n = 3) treatment with prednisolone. The data are presented as the mean ± standard error of the mean. (B, C) Flow cytometric analysis of terminally differentiated erythroid cells from a control donor and from a patient with a deletion in chromosome 3q29 using antibodies against CD41, CD44, and CD235 before steroid treatment (B) and after steroid treatment (C).