Table 5.

Gut tolerability in response to the placebo-control arm

(Mean values, standard deviations and ranges; n 9 per treatment arm)

	Run-in				Intervention
GI symptoms	Mean	sd	Minimum	Maximum	Mean	sd	Minimum	Maximum
Overall GI	0·8	1·0	0·0	2·5	0·3	0·4	0·0	1·2
Bothersome	0·6	0·7	0·0	2·0	0·2	0·2	0·0	0·5
Stomach rumble	0·2	0·7	0·0	2·3	0·1	0·2	0·0	0·6
Gut rumble	0·3	0·7	0·0	2·0	0·1	0·1	0·0	0·2
Belching	0·0	0·1	0·0	0·2	0·1	0·1	0·0	0·2
Nausea	0·0	0·1	0·0	0·3	0·0	0·0	0·0	0·1
Stomach cramps	0·1	0·2	0·0	0·5	0·0	0·0	0·0	0·1
Gut cramps	0·0	0·1	0·0	0·3	0·0	0·1	0·0	0·1
Bloated	0·5	0·7	0·0	2·3	0·1	0·2	0·0	0·4
Acid reflux	0·0	0·0	0·0	0·0	0·0	0·1	0·0	0·2
Flatulence	0·3	0·5	0·0	1·5	0·3	0·4	0·0	1·1
Diarrhoea	0·0	0·0	0·0	0·0	0·0	0·0	0·0	0·1
Vomiting	0·0	0·0	0·0	0·0	0·0	0·0	0·0	0·0
Constipation	0·3	0·6	0·0	2·0	0·0	0·0	0·0	0·1

GI, gastrointestinal.