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Survival of hepatitis C virus (HCV) replicon-containing cells during passage in ribavirin (RBV). Huh-7 cells containing HCV replicons were passaged in 0 or 100 μM RBV for 4 weeks, as indicated at the left. Cell lines were then passaged in 200, 300, or 400 μM RBV for 2 weeks, and cells were stained with crystal violet.
