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. 2017 Apr 17;114(22):E4442–E4451. doi: 10.1073/pnas.1618714114

Table S4.

NTP concentrations for several mutants

Relevant genotype CTP UTP ATP GTP
WT 2,360 ± 532 (1.0) 5,384 ± 1,406 (1.0) 12,088 ± 2,351 (1.0) 3,705 ± 912 (1.0)
pol1-L868M 2,440 ± 483 (1.0) 5,704 ± 942 (1.1) 12,310 ± 2,029 (1.0) 3,719 ± 669 (1.0)
pol2-M644G 2,825 ± 1,171 (1.2) 5,959 ± 2,511 (1.1) 15,418 ± 6,078 (1.3) 4,443 ± 1,902 (1.2)
pol3-L612M 2,870 ± 1,085 (1.2) 6,654 ± 2,626 (1.2) 15,524 ± 5,465 (1.3) 4,529 ± 1,765 (1.2)
gln3Δ 1,267 ± 443 (0.5). 8,957 ± 2,458 (1.7) 13,167 ± 3,592 (1.1) 2,929 ± 1,130 (0.8)
shm2Δ 3,411 ± 1,485 (1.4) 7,302 ± 3,243 (1.4) 17,439 ± 7,467 (1.4) 5,243 ± 2,429 (1.4)
ura7Δ 808 ± 288 (0.3) 6,575 ± 1,225 (1.2) 13,080 ± 1,958 (1.1) 3,587 ± 745 (1.0)
dun1Δ gln3Δ* 1,645 ± 172 (0.7) 7,533 ± 2,824 (1.4) 12,246 ± 1,371 (1.0) 3,272 ± 246 (0.9)
dun1Δ ura7Δ* 1,160 ± 81 (0.5) 8,338 ± 874 (1.5) 14,723 ± 502 (1.2) 4,151 ± 119 (1.1)

Relates to Fig. 4. NTP concentrations (in picomoles per 108 cells) are the average of two biological replicates ± SD with the fold increase over WT in parentheses.

*

NTP concentrations were measured at a different time point and normalized according to a WT strain included in the same run.