TABLE 2.
Comparison of putative CNGV-derived peptides by using Blastx
| Clone (accession no.) | Family | Genus | Protein | Accession no. | Identity (no. of amino acids with identity/total no. of amino acids [%]) | Conservation (no. of conserved amino acids/total no. of amino acids [%]) | Gaps (no. of gaps/total no. of amino acids [%]) |
|---|---|---|---|---|---|---|---|
| A (AY208988) | Herpesviridae | Ictalurid herpesvirus 1 | Hypothetical protein ORF56 | NP041147 | 37/138 (26) | 57/138 (41) | |
| B (AY208989) | Baculoviridae | Spodoptera littoralis nucleopolyhedrovirus | Ribonucleotide reductase | CAA67423 | 74/163 (45) | 102/163 (62) | |
| Poxviridae | Monkeypox virus | 14L | NP536492 | 74/162 (45) | 101/162 (62) | ||
| Poxviridae | Variola virus | Ribonucleoside-diphosphate reductase large chain | NP042102 | 74/162 (45) | 99/162 (61) | ||
| Poxviridae | Ectromelia virus | EVM057 | NP671575 | 73/162 (45) | 99/162 (61) | ||
| Baculoviridae | Ecotropis obliqua nucleopolyhedrovirus | Ribonucleotide reductase | AAQ88175 | 64/123 (52) | 90/123 (73) | ||
| Poxviridae | Vaccinia virus (strain WR) | Ribonucleoside-diphosphate reductase large chain | WZVZH4 | 73/162 (45) | 98/162 (60) | ||
| Poxviridae | Camelpox virus | Ribonucleotide reductase large subunit | NP570461 | 73/162 (45) | 98/162 (60) | ||
| Nimaviridae | Shrimp white spot syndrome virus | Ribonucleotide reductase large subunit | AAK69359 | 64/181 (35) | 98/181 (54) | 18/181 (9) | |
| Asfarviridae | African swine fever virus (strain Malawi) | Ribonucleoside-diphosphate reductase large chain | P26685 | 45/109 (41) | 69/109 (63) | ||
| Iridoviridae | Invertebrate iridescent virus 6 | Ribonucleoside-diphosphate reductase large chain | NP149548 | 48/113 (42) | 75/113 (66) | 4/113 (3) | |
| Herpesviridae | Equine herpesvirus 1a | Ribonucleoside-diphosphate reductase large chain | NP041030 | 38/70 (54) | 51/70 (72) | 1/70 (1) | |
| C (AY208990) | Poxviridae | Cowpox virus | CPXV083 | NP619870 | 124/190 (65) | 151/190 (79) | |
| Poxviridae | Camelpox virus | Ribonucleotide reductase large subunit | NP570461 | 126/190 (66) | 151/190 (79) | ||
| Poxviridae | Variola virus | Ribonucleoside diphosphate reductase large chain | NP042102 | 123/190 (64) | 150/190 (78) | ||
| Poxviridae | Vaccinia virus (strain WR) | Ribonucleosite reductase large subunit | P12848 | 124/190 (65) | 149/190 (78) | ||
| Nimaviridae | Shrimp white spot syndrome virus | Large subunit of ribonucleotide reductase | NP477694 | 104/193 (53) | 143/193 (74) | 1/193 (0) | |
| Asfarviridae | African swine fever virus (strain Malawi) | Ribonucleoside-diphosphate reductase large chain | P26685 | 78/203 (38) | 107/203 (52) | 19/203 (9) | |
| Herpesviridae | Meleagrid herpesvirus 1a | UL39 ribonucleotide reductase large subunit | NP073333 | 62/168 (36) | 90/168 (53) | 1/168 (0) | |
| D (AY208991) | Poxviridae | Yaba-like disease virus | 135R protein | NP073520 | 24/74 (32) | 36/74 (48) | 2/74 (2) |
| Herpesviridae | Human herpesvirus 8a | K1 glycoprotein | AAD26403 | 17/66 (25) | 34/66 (51) | ||
| E (AY661550) | Poxviridae | Yaba monkey tumor virus | 135R protein serine protease inhibitor | NP938338 | 21/55 (38) | 30/55 (54) | |
| Poxviridae | Myxoma virus | M134R protein | NP051848 | 19/56 (33) | 29/56 (51) | ||
| Poxviridae | Swinepox virus | SPV131 VAR B22R homologue | NP57029.1 | 19/56 (33) | 29/56 (51) | ||
| Poxviridae | Lumpy skin disease virus | LD131 | AAN02720.1 | 18/56 (32) | 32/56 (57) | ||
| Poxviridae | Rabbit fibroma virus | gp134R | NP052023.1 | 19/56 (33) | 29/56 (51) | ||
| Poxviridae | Sheeppox virus | VARV B22R homologue | NP659705.1 | 18/56 (32) | 35/56 (57) | ||
| Poxviridae | Molluscom contagiosum virus | MCO35R | NP043986.1 | 15/35 (42) | 23/35 (65) | ||
| Poxviridae | Cowpox virus | B7.5R | AAB57929.1 | 17/55 (30) | 31/55 (56) | ||
| Herpesviridae | Human herpesvirus 8 | ORF17 capsid assembly protein homologue | AAB62670 | 12/27 (44) | 16/27 (59) |
a
In general, similarity to Herpesviridae was not significant, but Herpesviridae is represented in the table as the most similar member of the family.