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. Author manuscript; available in PMC: 2018 Jan 11.
Published in final edited form as: J Am Chem Soc. 2016 Dec 22;139(1):409–416. doi: 10.1021/jacs.6b11087

Figure 3.

Figure 3

(A) Relative fluorescence measurements of RNA training set constructs in the presence of kanamycin. All titrations were performed in 10 mM NaH2PO4, 25 mM NaCl, 4 mM MgCl2, 0.5 mM EDTA, pH 7.3 buffer, at 25 °C from 0 to 4 μM aminoglycoside concentration. The titrations were performed in triplicate and averaged for input to PCA. Error bars have been removed for clarity, and error analysis can be found in Table S4-1. Remaining curves can be found in Figure S4-2. (B) PCA plot with nine commercially available aminoglycosides. The predictive power of the PCA plot is 87%. Ovals indicate 95% confidence intervals for each cluster.