Table 1. Demographic and clinical characteristics of sample (N = 100).
| Variable | All (N = 100) | HIV+ (n = 66) | HIV- (n = 34) | p-value | Effect size |
|---|---|---|---|---|---|
| Descriptive demographics | |||||
| Age, mean (SD) | 57.8 (6.0) | 57.3 (6.1) | 58.8 (5.9) | .26 | -.25 |
| Education, mean (SD) | 14.3 (2.7) | 14.3 (2.7) | 14.2 (2.7) | .80 | .04 |
| Male, n (%) | 78 (78.0%) | 56 (84.8%) | 22 (64.7%) | .02 | 3.05 |
| Non-Hispanic White, n (%) | 73 (73.0%) | 52 (78.8%) | 21 (61.8%) | .07 | .43 |
| Medical comorbidities and anthropometric measurement | |||||
| Hyperlipidemia, n (%) | 43 (44.3%) | 33 (52.4%) | 10 (29.4%) | .03 | 2.64 |
| Ever smoker, n (%) | 40 (41.2%) | 26 (41.3%) | 14 (41.2%) | .99 | 1.00 |
| Hypertension, n (%) | 37 (38.1%) | 24 (38.1%) | 13 (38.2%) | .99 | .99 |
| Current smoker, n (%) | 32 (33.0%) | 23 (36.5%) | 9 (26.5%) | .32 | 1.60 |
| Diabetes, n (%) | 19 (19.6%) | 13 (20.6%) | 6 (17.6%) | .72 | 1.21 |
| Hepatitis C Virus, n (%) | 18 (18.6%) | 12 (19.0%) | 6 (17.6%) | .87 | 1.10 |
| BMI, mean (SD) | 27.2 (5.3) | 26.9 (5.4) | 27.7 (5.1) | .45 | -.15 |
| Current Medications | |||||
| Lipid-lowering drug, n (%) | 30 (30.0%) | 23 (34.8%) | 7 (20.6%) | .14 | 2.06 |
| NSAID, n (%) | 28 (28.0%) | 20 (30.3%) | 8 (23.5%) | .47 | 1.41 |
| Antihypertensive, n (%) | 27 (27.0%) | 19 (28.8%) | 8 (23.5%) | .57 | 1.31 |
| Antidepressant, n (%) | 32 (32.0%) | 28 (42.4%) | 4 (11.8%) | <.01 | 5.52 |
| Psychiatric characteristics/diagnoses | |||||
| BDI-II total, median [IQR] | 6.0 [0.3-14.8] | 9.5 [2.8-16.3] | 1.5 [0.0-5.3] | <.01 | 0.86 |
| Current MDD, n (%) | 11 (11.1%) | 10 (15.4%) | 1 (2.9%) | .06 | 6.00 |
| LT MDD, n (%) | 48 (48.0%) | 38 (57.6%) | 10 (29.4%) | <.01 | 3.26 |
| LT alcohol use disorder, n (%) | 50 (50.0%) | 33 (50.0%) | 17 (51.5%) | .89 | .94 |
| LT cannabis use disorder, n (%) | 25 (25.3%) | 18 (27.3%) | 7 (21.2%) | .51 | 1.39 |
| LT meth use disorder, n (%) | 28 (28.3%) | 20 (30.3%) | 8 (24.2%) | .53 | 1.36 |
| HIV disease characteristics | |||||
| Years of infection, median [IQR] a | -- | 19.4 [11.3-25.5] | -- | -- | -- |
| AIDS, n (%) | -- | 41 (62.1%) | -- | -- | -- |
| Current CD4, median [IQR]b | -- | 654 [476-865] | -- | -- | -- |
| Nadir CD4, median [IQR] a | -- | 180 [41-300] | -- | -- | -- |
| Current PI use, n (%) c | -- | 31 (47.7%) | -- | -- | -- |
Note: BDI-II = Beck Depression Inventory – II; BMI = body mass index; LT = lifetime; MDD = major depressive disorder; NSAID = nonsteroidal anti-inflammatory drug; PI = protease inhibitor. Effect sizes are based on Hedge's g statistic for continuous variables and odds ratios for binary variables.
a
n = 64
b
n = 62
c
n = 65