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Composition of the six ligand solubilizing mixed cryosolutions (cryomixes) SM1-6 shown graphically as cylinders.
When used to formulate a cryoprotectant solution for crystal soaking, the cryomixes represent 40% of the volume, 10% is assigned to the buffer and 50% to the precipitant-water mixture that is 2× of the crystallization precipitant. For the solubilization of ligands, the cryomix is used directly to dissolve the ligand.
