Table 4.
Association between baseline anxiety symptoms and substantial cognitive impairment at visit 3 in older men
Anxiety symptoms | 3MS score decline of five points or more | Trails B worst decile of change | |||
---|---|---|---|---|---|
Unadjusted | Multivariable-adjusted* | Unadjusted | Multivariable-adjusted** | ||
Odds ratio (95% confidence interval) | |||||
Model 1 | Any | 1.12 (0.91, 1.39) |
1.07 (0.85, 1.35) |
1.56 (1.19, 2.05) |
1.40 (1.04, 1.88) |
None | 1.00 (reference) | ||||
Model 2 | Moderate/severe | 0.99 (0.67, 1.46) |
0.82 (0.53, 1.28) |
1.86 (1.19, 2.90) |
1.35 (0.81, 2.27) |
Mild | 1.17 (0.93, 1.47) |
1.13 (0.89, 1.44) |
1.47 (1.09, 1.99) |
1.41 (1.03, 1.93) |
|
None | 1.00 (reference) |
Models were adjusted for clinic site, age, depression, poor sleep, psychotropic medications, race, education, marital status and instrumental activities of daily living impairments.
Models were adjusted for clinic site, age, depression, poor sleep, psychotropic medications, race and instrumental activities of daily living impairments.