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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Int Psychogeriatr. 2017 Apr 9;29(7):1137–1145. doi: 10.1017/S104161021700045X

Table 4.

Association between baseline anxiety symptoms and substantial cognitive impairment at visit 3 in older men

Anxiety symptoms 3MS score decline of five points or more Trails B worst decile of change
Unadjusted Multivariable-adjusted* Unadjusted Multivariable-adjusted**
Odds ratio (95% confidence interval)
Model 1 Any 1.12
(0.91, 1.39)
1.07
(0.85, 1.35)
1.56
(1.19, 2.05)
1.40
(1.04, 1.88)
None 1.00 (reference)
Model 2 Moderate/severe 0.99
(0.67, 1.46)
0.82
(0.53, 1.28)
1.86
(1.19, 2.90)
1.35
(0.81, 2.27)
Mild 1.17
(0.93, 1.47)
1.13
(0.89, 1.44)
1.47
(1.09, 1.99)
1.41
(1.03, 1.93)
None 1.00 (reference)
*

Models were adjusted for clinic site, age, depression, poor sleep, psychotropic medications, race, education, marital status and instrumental activities of daily living impairments.

**

Models were adjusted for clinic site, age, depression, poor sleep, psychotropic medications, race and instrumental activities of daily living impairments.