Table 2.
Comparison of ICU survivors with and without prolonged mechanical ventilation for 7 days or longer
Prolonged ventilatory support | NO prolonged ventilation | ||
---|---|---|---|
N = 28 | N = 23 | P-value | |
Age, years | 56.9 (50.2, 67.8) | 59.4 (54.3, 75.0) | 0.18 |
Male gender, n (%) | 18 (64.3%) | 15 (65.2%) | 0.94 |
MICU, n (%) | 18 (64.3%) | 15 (65.2%) | 0.94 |
Diabetes mellitus, n (%) | 8 (28.6%) | 11 (47.8%) | 0.16 |
Hypertension, n (%) | 12 (42.9%) | 19 (82.6%) | 0.004 |
IHD, n (%) | 3 (10.7%) | 10 (43.5%) | 0.008 |
Chronic liver disease or liver cirrhosis, n (%) | 1 (3.6%) | 2 (8.7%) | 0.58 |
APACHE II score | 23 (20, 28) | 23 (18, 25) | 0.82 |
Time from hospital admission to ICU admission, days | 1 (0, 3) | 1 (0, 10) | 0.80 |
Premorbid serum creatinine, µmol/L | 87 (65, 97) | 108 (70, 154) | 0.12 |
AKI cause: sepsis, n (%) | 21 (87.5%) | 17 (89.5%) | 1.00 |
Oliguria, n (%) | 21 (75.0%) | 14 (77.8%) | 1.00 |
Mechanical ventilation at ICU admission, n (%) | 27 (96.4%) | 18 (94.7%) | 1.00 |
Vasopressor at ICU admission, n (%) | 23 (82.1%) | 12 (63.2%) | 0.18 |
Serum creatinine at RRT initiation, µmol/L | 256 (164, 354) | 311 (184, 539) | 0.28 |
Serum calcium at RRT initiation, mmol/L | 1.76 (1.62, 1.89) | 1.85 (1.9, 1.98) | 0.29 |
Serum phosphate at RRT initiation, mmol/L | 1.30 (0.96, 2.09) | 1.76 (1.63, 2.74) | 0.03 |
Serum albumin at RRT initiation, g/L | 23 (16, 24) | 23 (17, 28) | 0.14 |
Initial modality: CRRT, n (%) | 22 (78.6%) | 16 (69.6%) | 0.46 |
Effluent flow rate in CRRT, mL/kg/h | 34.4 (28.1, 40.0) | 33.0 (26.8, 37.3) | 0.51 |
CRRT duration, days | 1 (0, 4) | 3 (0, 5) | 0.17 |
Intermittent dialysis sessions, n (%) | 2 (0, 6) | 1 (0, 4) | 0.45 |
Total dialysis duration, days | 7 (4, 11) | 5 (4, 8) | 0.13 |
Hypophosphatemia during dialysis, n (%) | 14 (50.0%) | 2 (8.7%) | 0.002 |
Categorical variables are expressed as number (percentage) and compared using chi-square or Fisher’s exact test as appropriate. Continuous variables are expressed as median (IQR) and compared using Mann–Whitney U-test. MICU, medical intensive care unit.