Table 1.

Potential food and nutraceutical application of plastein.

Potential applications	Notes	References
Improvement of the nutritional value of proteins	Essential amino acids can be incorporated into low-quality proteins by protease-induced plastein reaction	[4], [43], [56], [58], [59]
Enhancement of chemosensory properties of protein hydrolysates and peptides	Bitterness-contributing hydrophobic amino acid residues can be hidden in the plastein core thereby limiting interaction with bitter taste receptors	[37], [38], [43]
Biological activities
Antihypertensive	In vitro inhibition of angiotensin I-converting enzyme activity	[19], [41], [53]
Antioxidative	In vitro radical scavenging, metal chelating and lipid peroxidation inhibitory activities	[47], [63]
	Cytoprotection against H2O2- and galactosamine-induced damage to rat hepatocyte (BRL) culture	[62]
Antithrombotic	In vitro inhibition of platelet aggregation (anticoagulation) based on activated partial thromboplastin and prothrombin time	[60]