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. 2017 Jun 7;13:1744806917707127. doi: 10.1177/1744806917707127

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Chronic compression of C7/8 DRGs induces dramatic mechanical hypersensitivity, slight thermal hyperalgesia, and frequent spontaneous nociception in rats. (a) Magnitude and time course of mechanical hypersensitivity (allodynia and hyperalgesia) to plantar Von Frey filaments application observed in CRP rats as compared to sham rats. (b) Showing the development of slight thermal hyperalgesia to radiant heat stimuli in CRP rats. (c) Development of spontaneous nociception in CRP rats, manifesting as lifting, licking, biting of the injured forepaws. Duration of the time spent in all these behaviors was recorded. All data are expressed as mean ± SEM. *P < 0.05 as compared to their basal levels using repeated measures one-way analysis of variance.

CRP: cervical radiculopathic pain.