Table 6. Performances of multivariable models in characterizing csPCa-C in PZ.
| AUC (95%CI)–Reader 1 | AUC (95%CI)–Reader 1 | |||
|---|---|---|---|---|
| With DCE | Without DCE | With DCE | Without DCE | |
| ST2 | 0.734 (0.662–0.794) | 0.628 (0.560–0.693) | ||
| SDWI | 0.751 (0.670–0.819) | 0.678 (0.617–0.742) | ||
| SDCE | 0.714 (0.640–0.791) | 0.660 (0.584–0.735) | ||
| S_max | 0.793 (0.713–0.863) | 0.752 (0.679–0.823) | 0.749 (0.674–0.823) | 0.706 (0.628–0.781) |
| S_min | 0.624 (0.583–0.666) | 0.562 (0.537–0.587) | ||
| Shape | 0.685 (0.611–0.770) | 0.685 (0.596–0.779) | ||
| ECE | 0.809 (0.727–0.880) | 0.824 (0.757–0.892) | ||
| Vmax | 0.752 (0.680–0.830) | 0.750 (0.670–0.828) | ||
| dPSA | 0.594 (0.448–0.675) | 0.614 (0.477–0.698) | ||
| Signal1 | 0.809 (0.731–0.875) | 0.768 (0.699–0.837) | 0.763 (0.690–0.829) | 0.710 (0.636–0.783) |
| Signal2 | 0.769 (0.694–0.842) | 0.766 (0.680–0.840) | 0.762 (0.692–0.829) | 0.709 (0.638–0.785) |
| Signal3 | 0.802 (0.739–0.878) | 0.782 (0.716–0.851) | 0.751 (0.685–0.831) | 0.706 (0.635–0.783) |
| Signal1 + Shape | 0.798 (0.719–0.875) | 0.770 (0.690–0.851) | 0.770 (0.703–0.850) | 0.729 (0.659–0.821) |
| Signal1 + ECE | 0.836 (0.768–0.903) | 0.825 (0.766–0.898) | 0.835 (0.776–0.894) | 0.833 (0.774–0.898) |
| Signal1 + Vmax | 0.831 (0.763–0.896) | 0.806 (0.742–0.880) | 0.818 (0.757–0.886) | 0.804 (0.732–0.877) |
| Signal1 + dPSA | 0.816 (0.748–0.880) | 0.784 (0.713–0.855) | 0.780 (0.710–0.854) | 0.742 (0.664–0.824) |
| Signal + Shape + ECE | 0.819 (0.747–0.895) | 0.814 (0.749–0.887) | 0.816 (0.756–0.885) | 0.814 (0.754–0.886) |
| Signal1 + Shape + Vmax | 0.820 (0.752–0.890) | 0.800 (0.737–0.877) | 0.806 (0.748–0.881) | 0.788 (0.723–0.867) |
| Signal1 + Shape + dPSA | 0.801 (0.730–0.875) | 0.780 (0.708–0.858) | 0.775 (0.711–0.859) | 0.742 (0.673–0.834) |
| Signal1 + ECE + Vmax | 0.839 (0.774–0.906) | 0.829 (0.771–0.899) | 0.839 (0.784–0.902) | 0.843 (0.781–0.907) |
| Signal1 + ECE + dPSA | 0.840 (0.774–0.907) | 0.833 (0.776–0.902) | 0.836 (0.779–0.897) | 0.835 (0.777–0.901) |
| Signal1 + Vmax + dPSA | 0.829 (0.764–0.895) | 0.806 (0.743–0.881) | 0.816 (0.757–0.887) | 0.802 (0.733–0.874) |
| Signal1 + Shape + ECE + Vmax | 0.825 (0.757–0.902) | 0.818 (0.760–0.893) | 0.824 (0.770–0.893) | 0.823 (0.763–0.897) |
| Signal1 + Shape + ECE + dPSA | 0.820 (0.754–0.899) | 0.817 (0.757–0.894) | 0.817 (0.755–0.888) | 0.815 (0.758–0.887) |
| Signal1 + Shape + Vmax + dPSA | 0.817 (0.752–0.891) | 0.801 (0.736–0.881) | 0.804 (0.746–0.880) | 0.786 (0.723–0.868) |
| Signal1 + ECE + Vmax + dPSA | 0.839 (0.775–0.905) | 0.833 (0.778–0.902) | 0.838 (0.786–0.904) | 0.839 (0.779–0.905) |
| Signal1 + Shape + ECE + Vmax + dPSA | 0.823 (0.755–0.902) | 0.819 (0.763–0.895) | 0.823 (0.767–0.897) | 0.822 (0.763–0.896) |
DCE: dynamic contrast-enhanced imaging; AUC: area under the receiver operating characteristic curve with optimism correction; 95%CI: 95% confidence intervals.
For each reader, the models achieving the highest AUC value were highlighted in green. The models achieving an AUC value that was inferior to the highest AUC value by 0.01 or less were highlighted in yellow.
Bold characters indicate models that performed better without DCE imaging.