Table 2.

Nucleotide frequency analysis of the 20 most highly cleaved sites formed by BLM and the analogues with the RTGTAY plasmid.

		−3	−2	−1	0	+1	+2
BLM	G	10	5	100	0	0	20
	A	10	0	0	0	100	35
	T	60	70	0	100	0	30
	C	20	25	0	0	0	15
6′-deoxy-BLM Z	G	0	0	100	0	0	15
	A	15	0	0	0	95	25
	T	65	85	0	95	0	35
	C	20	15	0	5	5	25
BLM Z	G	5	5	100	0	0	15
	A	10	0	0	0	90	30
	T	65	80	0	95	5	35
	C	20	15	0	5	5	20
ZBM	G	30	0	100	0	20	10
	A	15	0	0	0	75	10
	T	45	85	0	100	5	50
	C	10	15	0	0	0	30

The frequency of occurrence of each nucleotide was calculated at the −3, −2, −1, 0, +1 and +2 positions at the 20 most highly cleaved sites for BLM and the analogues with the RTGTAY plasmid and presented as a percentage for each compound. The values have been corrected for the frequency of occurrence of nucleotides in the analysed sequence.