Table II.
Functional enrichment analysis for the DEGs of the HM group.
| Term | Count | P-value | ||
|---|---|---|---|---|
| Up | BP | GO:0051186-cofactor metabolic process | 8 | 1.04E-03 |
| GO:0055114-oxidation reduction | 15 | 2.04E-03 | ||
| GO:0019748-secondary metabolic process | 5 | 3.02E-03 | ||
| CC | GO:0005576-extracellular region | 37 | 4.68E-06 | |
| GO:0005777-peroxisome | 5 | 2.03E-02 | ||
| GO:0042579-microbody | 5 | 2.03E-02 | ||
| MF | GO:0019842-vitamin binding | 10 | 1.64E-06 | |
| GO:0016290-palmitoyl-CoA hydrolase activity | 3 | 8.12E-03 | ||
| GO:0030170-pyridoxal phosphate binding | 4 | 1.33E-02 | ||
| KEGG | mmu03320:PPAR signaling pathway | 5 | 6.25E-03 | |
| mmu00590:Arachidonic acid metabolism | 5 | 7.43E-03 | ||
| Down | BP | GO:0042445-hormone metabolic process | 7 | 1.63E-04 |
| GO:0010817-regulation of hormone levels | 7 | 1.07E-03 | ||
| GO:0042398-cellular amino acid derivative biosynthetic process | 4 | 9.31E-03 | ||
| CC | GO:0005783-endoplasmic reticulum | 15 | 1.29E-02 | |
| MF | GO:0004866-endopeptidase inhibitor activity | 7 | 3.52E-03 | |
| GO:0030414-peptidase inhibitor activity | 7 | 5.43E-03 | ||
| GO:0004867-serine-type endopeptidase inhibitor activity | 5 | 2.09E-02 |
DEGs, differentially expressed genes; HM, hypertensive male; up, upregulated DGEs; down, downregulated DEGs; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto Encyclopedia of Genes and Genomes.