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. 2017 May 31;40(1):182–192. doi: 10.3892/ijmm.2017.3008

Figure 2.

Figure 2

LC3 and p-mTOR-are altered in HeLa cells at 24 h.p.i. HeLa cells were infected with CVB3. DMEM containing 2% FBS served as the sham control, and rapamycin (Rap) (100 µM) served as a positive control. At 24 h.p.i. cells were collected for western blot analysis. Compared with the sham group, the total amount of LC3 (LC3-I, LC3-II) and the ratio of LC3-II/LC3-I were markedly increased in the infected cells at 24 h.p.i. (p<0.05). The expression of p-mTOR was downregulated (p<0.05). *p<0.05, compared with the sham group; **p<0.01, compared with the sham group. LC3, light chain 3; mTOR, mammalian target of rapamycin; h.p.i., hours post-inoculation; CVB3, coxsackievirus B3; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovine serum.