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. 2017 May 9;40(1):90–100. doi: 10.3892/ijmm.2017.2981

Figure 2.

Figure 2

Surgery-induced anxiety and hyperactivity of the hypothalamic pituitary adrenal (HPA) axis following treatment with NBI-27914. (A) Rat performance in open field test. (B) Rat performance in elevated plus maze test. (C) Representative western blots of the hypothalamus CRHR1 are shown following treatment with NBI-27914. (D) CRH, adrenocorticotropic hormone (ACTH) and CORT levels in serum; n=7 for each group. *p<0.05 represents a statistically significant difference when compared with the hepatectomy + vehicle group.