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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Bone Miner Res. 2017 Mar 29;32(6):1332–1342. doi: 10.1002/jbmr.3112

Figure 2. Delayed Cdh2 ablation prevents the low bone mass phenotype present in mice with embryonic Cdh2 ablation.

Figure 2

(A) Representative μCT images of tibiae of 2-months-old, Doxycycline (Doxy)-fed, male Cdh2F/F and cKO-Osx mice. (B) Volumetric trabecular bone volume/total bone volume (BV/TV) and (C) trabecularization of the diaphysis, as percent of diaphyseal length in the two groups of animals. (D) Volumetric BV/TV, (E) trabecular number (Tb. N), and (F) cortical area at the mid-diaphysis measured by in vivo μCT in 2-month-old male Cdh2F/F and Cdh2Prx littermates (n=7, 8, respectively). Similar results (not shown) were observed in females *p<0.05 vs. Cdh2F/F, Student’s t-test.