Table 2b.
Model I | Model II | |||||
---|---|---|---|---|---|---|
n | β (95% CI)1 | p | n | β (95% CI)1 | p | |
RS-I | ||||||
Men | 1458 | −0.13 (−0.24 to −0.02) | 0.021 | 1437 | −0.10 (−0.21 to 0.01) | 0.084 |
Women | 2003 | −0.21 (−0.31 to −0.11) | <0.001 | 1943 | −0.09 (−0.19 to 0.01) | 0.084 |
RS-II | ||||||
Men | 910 | −0.19 (−0.34 to −0.04) | 0.012 | 906 | −0.18 (−0.32 to −0.03) | 0.017 |
Women | 1059 | −0.15 (−0.28 to −0.02) | 0.027 | 1051 | −0.02 (−0.15 to 0.11) | 0.730 |
RS-III | ||||||
Men | 766 | −0.12 (−0.27 to 0.03) | 0.126 | 766 | −0.09 (−0.24 to 0.06) | 0.238 |
Women | 1039 | −0.06 (−0.18 to 0.07) | 0.374 | 1038 | 0.02 (−0.10 to 0.14) | 0.772 |
RS combined2 | ||||||
Men | 3134 | −0.14 (−0.22 to −0.07) | <0.001 | 3109 | −0.12 (−0.19 to −0.04) | 0.002 |
Women | 4101 | −0.15 (−0.22 to −0.08) | <0.001 | 4032 | −0.04 (−0.10 to 0.03) | 0.247 |
MrOS | ||||||
Men | 5390 | −0.02 (−0.08 to 0.04) | 0.495 | 5387 | −0.03 (−0.09 to 0.03) | 0.360 |
Studies combined2 | ||||||
Men | 8524 | −0.07 (−0.11 to −0.02) | 0.005 | 8496 | −0.06 (−0.11 to −0.02) | 0.007 |
Women | 4101 | −0.15 (−0.22 to −0.08) | <0.001 | 4032 | −0.04 (−0.10 to 0.03) | 0.247 |
Sex-combined | 12625 | −0.10 (−0.13 to −0.06) | <0.001 | 12528 | −0.06 (−0.09 to −0.02) | 0.004 |
Model I: age adjusted
Model II: age, BMI and smoking adjusted; additional race and site adjustments in MrOS
Betas are expressed per 1 mg/dL increase in P levels; BMD is expressed in SD
Studies were pooled applying a fixed effects model